The OPP say the accident took place on the road to Grassy Narrows around 12:30 Sunday morning, about 30 kilometers north of the By-Pass.
Police say the vehicle drove off the road and hit a hydro pole.
Both of the occupants of the vehicle were transported by ambulence to Lake of the Woods District Hospital.
The driver, a 48 year old man sustained what are being called life-threatening injuries, and was transported by air ambulence to hospital in Winnipeg.